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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on protein-DNA interaction EZ-TFA transcription factor colorimetric assay 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM OVCAR-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM TOV-21G Homo sapiens STAT3
3,3 diindolylmethane Influence on protein-DNA interaction Luciferase activity 75.00 µM A2780 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in presence of IL-6 Western Blot 75.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protein activity in cells overexpressing STAT3 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis in presence of IL-6 Flow cytometry- annexin V binding and propidium iodide staining 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis in presence of IL-6 Flow cytometry- annexin V binding and propidium iodide staining 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on apoptosis in cells overexpressing STAT3 Flow cytometry- annexin V binding and propidium iodide staining 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Infleunce on cytokine secretion ELISA 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Infleunce on cytokine secretion ELISA 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Infleunce on cytokine secretion ELISA 75.00 µM OVCAR-429 Homo sapiens
3,3 diindolylmethane Influence on cell motility Wound healing assay 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Wound healing assay 50.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Wound healing assay 50.00 µM TOV-21G Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility Western Blot 75.00 µM OVCAR-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell motility in presence of IL-6 Western Blot 75.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of cisplatin SRB cell survival assay 20.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of cisplatin SRB cell survival assay 50.00 µM SKOV-3 Homo sapiens
3,3 diindolylmethane Influence on protin actiity in presence of cisplatin Western Blot 50.00 µM SKOV-3 Homo sapiens p-STAT3 (Y705)