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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
3,3 diindolylmethane Influence on cell proliferation in presence of PDGF WST-1 10.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell proliferation in presence of PDGF BrdU cell proliferation assay 10.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of PDGF Trypan blue dye exclusion assay 10.00 µM VSMC Homo sapiens
3,3 diindolylmethane Influence on cell viability in presence of PDGF Trypan blue dye exclusion assay 10.00 µM HUVECS Homo sapiens
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens STAT1
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens STAT1
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens p-STAT1 (Y701)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens p-STAT1 (Y701)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens STAT3
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens p-STAT3 (Y705)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens p-STAT3 (S727)
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens STAT5A
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens STAT5A
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens STAT5B
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens STAT5B
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on protein activity Western Blot 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens STAT1 (nucleus)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens p-STAT1 (nucleus)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens STAT3 (nucleus)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens p-STAT3 (nucleus)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens STAT1 (cytoplasm)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens p-STAT1 (cytoplasm)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens STAT3 (cytoplasm)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens p-STAT3 (cytoplasm)
3,3 diindolylmethane Infleunce on protein translocation Western Blot 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell motility Transwell Boyden Chamber; Hema Gurr rapid stain (BDH) 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell motility Transwell Boyden Chamber; Hema Gurr rapid stain (BDH) 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell adhesion Collagen adhesion assay 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell adhesion Collagen adhesion assay 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Caspase 3/7 activity 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Caspase 3/7 activity 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Caspase 3/7 activity 10.00 µM RT4 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis annexin V binding and propidium iodide staining 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis annexin V binding and propidium iodide staining 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM RT4 Homo sapiens PARP
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM J82 Homo sapiens PARP
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM RT112 Homo sapiens PARP
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM RT4 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell apoptosis Western Blot 10.00 µM RT112 Homo sapiens
3,3 diindolylmethane Influence on cell cycle Western Blot 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell cycle Western Blot 10.00 µM J82 Homo sapiens
3,3 diindolylmethane Influence on cell cycle Western Blot 10.00 µM RT112 Homo sapiens