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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 1.00 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM U251-MG Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on cell proliferation WST-1 Cell Proliferation Assay 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on cell proliferation WST-1 Cell Proliferation Assay 10.00 µM U251-MG Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry- annexin V staining 1.00 µM U251-MG Homo sapiens
AZD1480 Cell Apoptosis Analysis Flow cytometry- annexin V staining 10.00 µM U251-MG Homo sapiens
AZD1480 Cell Apoptosis Analysis Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Cell Apoptosis Analysis Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Cell Apoptosis Analysis Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Cell Apoptosis Analysis Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on cell motility Soft Agar Growth Assay 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on cell motility Soft Agar Growth Assay 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.10 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 0.50 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on protein activity in presence of OSM Western Blot 10.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens
AZD1480 Influence on downstream gene transcription RT-qPCR 1.00 µM U251-MG Homo sapiens