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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell proliferation SRB assay 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell cycle Flow cytometry 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis TUNEL 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM TPC-1 Homo sapiens
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 30.00 mg/kg TPC-1 (xenograft) Mus musclus
AZD1480 Influence on cell proliferation in tumor tissue Immunostaining 30.00 mg/kg TPC-1 (xenograft) Mus musclus nu/nu Nude mice
AZD1480 Influence on cell proliferation in tumor tissue Immunostaining 30.00 mg/kg TPC-1 (xenograft) Mus musclus nu/nu Nude mice
AZD1480 Influence on cell proliferation in tumor tissue Immunostaining 30.00 mg/kg TPC-1 (xenograft) Mus musclus nu/nu Nude mice