| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell cycle |
Flow cytometr- propodium iodide staining |
2.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell proliferation |
MTS Assay |
N/A N/A |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Caspase 3/7 activity |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Caspase 3/7 activity |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Caspase 3/7 activity |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on cell apoptosis |
Cell survival assay |
0.50 µM |
SY5Y |
|
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
2.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
5.00 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
0.50 µM |
SY5Y |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on STAT3 downstream genes |
Western Blot |
1.00 µM |
SY5Y |
Homo sapiens |
|
|
|
