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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell cycle Flow cytometr- propodium iodide staining 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on cell cycle Flow cytometr- propodium iodide staining 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on cell cycle Flow cytometr- propodium iodide staining 2.00 µM Rh18 Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on cell apoptosis Caspase 3/7 activity 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on cell apoptosis Cell survival assay 0.50 µM Rh18
AZD1480 Influence on protein activity Western Blot 0.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 5.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 1.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 5.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Rh18 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Rh18 Homo sapiens STAT3
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Rh18 Homo sapiens
AZD1480 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 0.50 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 1.00 µM Rh18 Homo sapiens
AZD1480 Influence on STAT3 downstream genes Western Blot 2.50 µM Rh18 Homo sapiens