| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.05 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
0.50 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
1.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
5.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on cell proliferation |
WST-8 |
20.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
STAT3 |
|
| Ponatinib |
Influence on protein activity |
Western Blot |
10.00 µM |
NB-19 |
Homo sapiens |
|
|
|
| Ponatinib |
Influence on tumor growth |
Tumor size |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on tumor growth |
Tumor weight |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
p-STAT3 (Y705) |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
STAT3 |
|
| Ponatinib |
Influence on protein activity in tumor tissue |
Western Blot |
15.00 mg/kg |
NB-19 (xenograft) |
Mus musculus |
NCr nude mice |
|
|
