| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
MDAH2774 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
MDAH2774 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MDAH2774 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.05 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.10 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.25 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
0.50 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity |
Western Blot |
1.00 µM |
MDAH2774 |
Homo sapiens |
|
|
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
3.00 µM |
MDAH2774 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in presence of IL-6 |
Western Blot |
0.30 µM |
MDAH2774 |
Homo sapiens |
|
STAT3 |
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
1.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
10.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
p-STAT3 (Y705) |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
STAT3 |
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
| AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
MDAH2774 (xenograft) |
Mus musculus |
|
|
|
