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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell apoptosis Western Blot 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell proliferation Colony formation assay 1.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell proliferation Colony formation assay 2.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell proliferation Colony formation assay 5.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on cell proliferation Colony formation assay 10.00 µM MDA-MB-231 Homo sapiens
STAT3-IN-1 (compound 7d) Influence on tumor growth Mice body weight 10.00 mg/kg MDA-MB-231(xenograft) Mus musculus
STAT3-IN-1 (compound 7d) Influence on tumor growth Mice body weight 20.00 mg/kg MDA-MB-231(xenograft) Mus musculus
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg MDA-MB-231(xenograft) Mus musculus p-STAT3(Y705)
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 20.00 mg/kg MDA-MB-231(xenograft) Mus musculus p-STAT3(Y705)
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg MDA-MB-231(xenograft) Mus musculus STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 20.00 mg/kg MDA-MB-231(xenograft) Mus musculus STAT3
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 10.00 mg/kg MDA-MB-231(xenograft) Mus musculus
STAT3-IN-1 (compound 7d) Influence on protein activity in tumor tissue Western Blot 20.00 mg/kg MDA-MB-231(xenograft) Mus musculus