| SH5-07 |
Influence on protein binding to DNA |
EMSA |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
8.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Influence on protein binding to DNA |
EMSA |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
| SH5-07 |
Infleunce on protein activity |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH5-07 |
Influence on cell viability |
CyQUANT cell proliferation assay |
2.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell viability |
CyQUANT cell proliferation assay |
4.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell viability |
CyQUANT cell proliferation assay |
6.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell viability |
CyQUANT cell proliferation assay |
8.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell viability |
CyQUANT cell proliferation assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell motility |
Colony formation assay |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell motility |
Colony formation assay |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell cycle |
Flow cytometry- propodium iodide |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell cycle |
Flow cytometry- propodium iodide |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell cycle |
Flow cytometry- propodium iodide |
8.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell apoptosis |
Flow cytomentry- Annexin V |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell apoptosis |
Flow cytomentry- Annexin V |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on cell apoptosis |
Flow cytomentry- Annexin V |
8.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on expression of proteins downstream target genes |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH5-07 |
Influence on tumor growth |
Tumor size |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH5-07 |
Influence on tumor growth |
Tumor size |
3.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH5-07 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH5-07 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH5-07 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
