| SH4-54 |
Influence on protein binding to DNA |
EMSA |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH4-54 |
Influence on protein binding to DNA |
EMSA |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH4-54 |
Influence on protein binding to DNA |
EMSA |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH4-54 |
Influence on protein binding to DNA |
EMSA |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3:STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on protein activty |
Western Blot |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on proetin acivity in presnce of IL-6 |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
p-STAT3(Y705) |
|
| SH4-54 |
Influence on proetin acivity in presnce of IL-6 |
Western Blot |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
STAT3 |
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
2.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
4.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
6.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
8.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
CyQUANT cell proliferation assay |
10.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
Colony formation assay |
1.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
Colony formation assay |
3.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on cell viability |
Colony formation assay |
5.00 µM |
MDA-MB-231 |
Homo sapiens |
|
|
|
| SH4-54 |
Influence on tumor growth |
Tumor size |
6.00 mg/kg |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
4.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
4.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
3.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
4.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
| SH4-54 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 µM |
MDA-MB-231 (xenograft) |
Mus musculus |
athymic nude mice |
|
|
