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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Western Blot 0.05 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.10 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.25 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.50 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 1.00 µM LN-17 Homo sapiens p-STAT3 (Y705)
AZD1480 Influence on protein activity Western Blot 0.05 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.25 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on protein activity Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on protein-DNA interaction EMSA 0.10 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 Influence on protein-DNA interaction EMSA 0.50 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 Influence on protein-DNA interaction EMSA 1.00 µM LN-17 Homo sapiens STAT3:STAT3
AZD1480 Influence on cell viability MTS Assay 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell viability MTS Assay 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Flow cytometry- annexin V staining 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Flow cytometry- annexin V staining 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Flow cytometry- annexin V staining 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.10 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 0.50 µM LN-17 Homo sapiens
AZD1480 Influence on cell apoptosis Western Blot 1.00 µM LN-17 Homo sapiens