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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens STAT3
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens STAT3
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on downstream target genes Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Hep3B Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens p-STAT3 (Y705)
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Hep3B Homo sapiens STAT3
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens STAT3
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Hep3B Homo sapiens p-STAT1 (Y701)
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens p-STAT1 (Y701)
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 2.50 µM Hep3B Homo sapiens STAT1
OPB-31121 Influence on protein activity in presence of IL-6 Western Blot 5.00 µM Hep3B Homo sapiens STAT1
OPB-31121 Influence on cell viability MTT 1.00 µM Hep3B Homo sapiens
OPB-31121 Influence on cell viability MTT 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on cell viability MTT 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on cell viability MTT 7.50 µM Hep3B Homo sapiens
OPB-31121 Influence on cell proliferation Colony formation assay 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on cell proliferation Colony formation assay 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on cell motility Wound healing assay 2.50 µM Hep3B Homo sapiens
OPB-31121 Influence on cell motility Wound healing assay 5.00 µM Hep3B Homo sapiens
OPB-31121 Influence on protein translocation Immunofluorescence 5.00 µM Hep3B Homo sapiens STAT3