OPB-31121 |
Influence on tumor growth |
Tumor volume |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
p-STAT3 (Y705) |
|
OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
STAT3 |
|
OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
OPB-31121 |
Influence on protein activity in tumor tissue |
Western Blot |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
|
|
OPB-31121 |
Influence on cell apoptosis |
TUNEL |
5.00 mg/kg |
HCT116 (xenograft) |
Mus musculus |
nude mice |
STAT3 |
|