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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on protein activity Immunoprecipitation 15.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 30.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 60.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 100.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 200.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 300.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 400.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Immunoprecipitation 15.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 30.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 60.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 100.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 200.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 300.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 400.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 5.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 10.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 20.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 30.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 60.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 100.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 200.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 400.00 nM CWR22Pc Homo sapiens STAT5A
AZD1480 Influence on protein activity Western Blot 5.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 10.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 20.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 30.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 60.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 100.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 200.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on protein activity Western Blot 400.00 nM CWR22Pc Homo sapiens STAT5B
AZD1480 Influence on cell proliferation MTS Assay 1.00 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis FACS 0.50 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis FACS 1.00 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis FACS 1.50 µM CWR22Pc Homo sapiens
AZD1480 Influence on cell apoptosis Fluorometric immunosorbent enzyme assay 800.00 nM CWR22Pc Homo sapiens
AZD1480 Influence on cell proliferation in tumor tissue Tumour volume 10.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on cell proliferation in tumor tissue Tumour volume 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on protein activity Immunohistochemistry 30.00 mg/kg CWR22Pc Mus musculus STAT5A
AZD1480 Influence on protein activity Immunohistochemistry 30.00 mg/kg CWR22Pc Mus musculus STAT5B
AZD1480 Influence on protein activity Immunoprecipitation 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on protein activity Western Blot 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on cell proliferation Hematoxylin-eosin staining 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on protein activity Western Blot 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on protein activity Western Blot 30.00 mg/kg CWR22Pc Mus musculus
AZD1480 Influence on protein activity Western Blot 30.00 mg/kg CWR22Pc Mus musculus