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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Momelotinib (CYT387) Influence on cell growth Trypan blue exclusion assay 1.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell growth Trypan blue exclusion assay 2.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell growth Trypan blue exclusion assay 5.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell growth MTS 1.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell growth MTS 2.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell growth MTS 5.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation CellTiter96 AQueous One Solution Cell Proliferation assays 1.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation CellTiter96 AQueous One Solution Cell Proliferation assays 2.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation CellTiter96 AQueous One Solution Cell Proliferation assays 5.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation MTS 2.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation MTS 4.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation MTS 6.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell proliferation MTS 8.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on RNA expression RT-qPCR N/A µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on RNA expression RT-qPCR N/A µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on protein activity Western Blot 1.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on protein activity Western Blot 2.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on protein activity Western Blot 5.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on protein activity Western Blot 1.00 µM CLBL-1 Canis familriaris p-STAT3
Momelotinib (CYT387) Influence on protein activity Western Blot 2.00 µM CLBL-1 Canis familriaris p-STAT3
Momelotinib (CYT387) Influence on protein activity Western Blot 5.00 µM CLBL-1 Canis familriaris p-STAT3
Momelotinib (CYT387) Influence on protein activity Western Blot 1.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on protein activity Western Blot 2.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on protein activity Western Blot 5.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on STAT3 activity in presence of IL6 Flow cytometry 1.50 µM CLBL-1 Canis familriaris p-STAT3
Momelotinib (CYT387) Influence on STAT3 activity in presence of IL6 MFI 1.50 µM CLBL-1 Canis familriaris p-STAT3
Momelotinib (CYT387) Influence on cell apoptosis Flow cytometry 1.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell apoptosis Flow cytometry 5.00 µM CLBL-1 Canis familriaris
Momelotinib (CYT387) Influence on cell cycle Ki67/DAPI cell proliferation assay 1.00 µM CLBL-1 Canis familriaris