Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
0.30 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
1.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
3.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding |
Cell-free assay |
30.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding in presence of EGF |
Fluorescence polarization assay |
0.30 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding in presence of EGF |
Fluorescence polarization assay |
1.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding in presence of EGF |
Fluorescence polarization assay |
3.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding in presence of EGF |
Fluorescence polarization assay |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein binding in presence of EGF |
Fluorescence polarization assay |
30.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
3.00 µM |
A375 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
20.00 µM |
A375 |
Homo sapiens |
|
p-STAT3 (Y705) |
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
3.00 µM |
A375 |
Homo sapiens |
|
STAT3 |
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
STAT3 |
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
20.00 µM |
A375 |
Homo sapiens |
|
STAT3 |
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
3.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
10.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Western Blot |
20.00 µM |
A375 |
Homo sapiens |
|
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Average tumor volume |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Average body weight |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Mean tumor weight |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on tumor growth |
Mean organ weight |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Immunohistochemistry |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Immunohistochemistry |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on protein activity |
Immunohistochemistry |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|
Cyclometalated rhodium(III) complex 12 |
Influence on blood flow |
Laser Doppler flowmetry |
75.00 mg/kg |
A375(xenograft) |
Mus musculus |
BALB/c |
|
|