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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
Toosendanin Influence on expression of STAT3 target genes RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes RT-PCR 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 100.00 nM 143B Homo sapiens
Toosendanin Influence on protein activity Western Blot 200.00 nM 143B Homo sapiens
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 50.00 nM 143B Homo sapiens STAT3:Bcl2
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 100.00 nM 143B Homo sapiens STAT3:Bcl2
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 200.00 nM 143B Homo sapiens STAT3:Bcl2
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 50.00 nM 143B Homo sapiens STAT3:VEGF
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 100.00 nM 143B Homo sapiens STAT3:VEGF
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 200.00 nM 143B Homo sapiens STAT3:VEGF
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 50.00 nM 143B Homo sapiens STAT3:SOCS3
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 100.00 nM 143B Homo sapiens STAT3:SOCS3
Toosendanin Influence on protein-DNA interaction Chromatin immunoprecipitation assay 200.00 nM 143B Homo sapiens STAT3:SOCS3
Toosendanin Influence on cell viability MTS Assay 25.00 nM 143B Homo sapiens
Toosendanin Influence on cell viability MTS Assay 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell viability MTS Assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell viability MTS Assay 200.00 nM 143B Homo sapiens
Toosendanin Influence on cell viability in STAT3 transfected cells MTS Assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on expression of STAT3 target genes in STAT3 transfected cells RT-PCR 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Colony formation assay 25.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell apoptosis Flow cytometry- annexin V binding and propidium iodide staining 200.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 25.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility Invasion assay 200.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 50.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 100.00 nM 143B Homo sapiens
Toosendanin Influence on cell motility 3D culture assay 200.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 50.00 nM 143B Homo sapiens
Toosendanin Influence on EMT Western Blot 100.00 nM 143B Homo sapiens