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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on late protein activity in tumor tissue Western Blot 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on tumor growth Histological staining 30.00 mg/kg KCNR (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on tumor growth Histological staining 30.00 mg/kg SY5Y (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on tumor growth Histological staining 30.00 mg/kg Rh18 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on tumor growth Histological staining 30.00 mg/kg TC32 (xenograft) Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.10 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 0.50 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on protein activity in tumor tissue in presence of OSM Western Blot 10.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Inhibition of protein signalling in human glioblastoma xenograft tumors RT-qPCR 1.00 µM Xenograft X1016 Mus musculus athymic nude mice
AZD1480 Inhibition of protein signalling in human glioblastoma xenograft tumors RT-qPCR 1.00 µM Xenograft X1016 Mus musculus athymic nude mice
AZD1480 Inhibition of protein signalling in human glioblastoma xenograft tumors RT-qPCR 1.00 µM Xenograft X1016 Mus musculus athymic nude mice
AZD1480 Inhibition of cell proliferation in xenograft tumors WST-1 Cell Proliferation Assay 10.00 µM Xenograft X1016 Mus musculus athymic nude mice
AZD1480 Influence on CD133 expression in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice p-STAT3 (Y705)
AZD1480 Influence on CD133 expression in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice STAT3
AZD1480 Influence on CD133 expression in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice
AZD1480 Influence on CD133 expression in tumor tissue in presence of OSM Western Blot 1.00 µM Xenograft X1066 Mus musculus athymic nude mice