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Experiments

Compound Investigated event Experiment type Concentration Cell line Organism Animal model Stat protein Details
AZD1480 Influence on cell proliferation in tumor tissue Tumor volume 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c p-STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c STAT3
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on protein activity in tumor tissue Western Blot 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on angiogenesis Immunostaining 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on angiogenesis Immunostaining 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on angiogenesis Immunostaining 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on angiogenesis Immunostaining 50.00 mg/kg Renca (xenograft0 Mus musclus BALB/c
AZD1480 Influence on cell motility Tube formation assay 0.10 µM EC Mus musclus BALB/c
AZD1480 Influence on cell motility Tube formation assay 0.50 µM EC Mus musclus BALB/c
AZD1480 Influence on cell motility Tube formation assay 1.00 µM EC Mus musclus BALB/c
AZD1480 Influence on cell motility Tube formation assay 0.10 µM HUVEC Homo sapiens BALB/c
AZD1480 Influence on cell motility Tube formation assay 0.50 µM HUVEC Homo sapiens BALB/c
AZD1480 Influence on cell motility Tube formation assay 1.00 µM HUVEC Homo sapiens BALB/c
AZD1480 Influence on tumor metastasis Number of nodules 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c p-STAT3
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c STAT3
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c
AZD1480 Influence on protein activity in metastatic tumor Western Blot 50.00 mg/kg Renca Mus musclus BALB/c