AZD1480 |
Influence on cell proliferation in tumor tissue |
Tumor volume |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
p-STAT3 |
|
AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
STAT3 |
|
AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on protein activity in tumor tissue |
Western Blot |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on angiogenesis |
Immunostaining |
50.00 mg/kg |
Renca (xenograft0 |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on cell motility |
Tube formation assay |
0.10 µM |
EC |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on cell motility |
Tube formation assay |
0.50 µM |
EC |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on cell motility |
Tube formation assay |
1.00 µM |
EC |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on cell motility |
Tube formation assay |
0.10 µM |
HUVEC |
Homo sapiens |
BALB/c |
|
|
AZD1480 |
Influence on cell motility |
Tube formation assay |
0.50 µM |
HUVEC |
Homo sapiens |
BALB/c |
|
|
AZD1480 |
Influence on cell motility |
Tube formation assay |
1.00 µM |
HUVEC |
Homo sapiens |
BALB/c |
|
|
AZD1480 |
Influence on tumor metastasis |
Number of nodules |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
p-STAT3 |
|
AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
STAT3 |
|
AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|
AZD1480 |
Influence on protein activity in metastatic tumor |
Western Blot |
50.00 mg/kg |
Renca |
Mus musclus |
BALB/c |
|
|