Investigated event: Influence on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | AS1810722 |
| Investigated event | Influence on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 0.30 µM |
| Cell line | fibroblast-like synoviocytes (FLS) |
| Organism | Homo sapiens (patient) |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
Auranofin blocks interleukin-6 signalling by inhibiting phosphorylation of JAK1 and STAT3. Immunology Nam-Hoon Kim, Mun-Yong Lee, Seon-Joo Park, Jeong-Sun Choi, Mi-Kyung Oh, In-Sook Kim, 122, 4, None, 2007-07-20, 10.1111/j.1365-2567.2007.02679.x
DOI: 10.1111/j.1365-2567.2007.02679.x
PUBMED: 17645497
PMCID: PMC2266044