Investigated event: Influence on protein activity in presence of imatinib

Name Value
Compound Pimozide
Investigated event Influence on protein activity in presence of imatinib
Experiment type Western Blot
Concentration 5.00 µM
Cell line KU812
Organism Homo sapiens
Animal model
STAT protein p-STAT5
Other
Reference
The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations. Genes & cancer Erik A Nelson, Sarah R Walker, Michael Xiang, Ellen Weisberg, Michal Bar-Natan, Rosemary Barrett, Suiyang Liu, Surender Kharbanda, Amanda L Christie, Maria Nicolais, James D Griffin, Richard M Stone, Andrew L Kung, David A Frank, 3, 7-8, None, None, 10.1177/1947601912466555 DOI: 10.1177/1947601912466555 PUBMED: 23264850 PMCID: PMC3527989