Investigated event: Influence on tumor growth
| Name | Value |
|---|---|
| Compound | Pimozide |
| Investigated event | Influence on tumor growth |
| Experiment type | Body weight |
| Concentration | 25.00 mg/kg |
| Cell line | Ba/f3 FLT3 ITD luc+ |
| Organism | Mus musculus |
| Animal model | NCr nude mice |
| STAT protein | |
| Other |
Reference
The STAT5 Inhibitor Pimozide Displays Efficacy in Models of Acute Myelogenous Leukemia Driven by FLT3 Mutations. Genes & cancer Erik A Nelson, Sarah R Walker, Michael Xiang, Ellen Weisberg, Michal Bar-Natan, Rosemary Barrett, Suiyang Liu, Surender Kharbanda, Amanda L Christie, Maria Nicolais, James D Griffin, Richard M Stone, Andrew L Kung, David A Frank, 3, 7-8, None, None, 10.1177/1947601912466555
DOI: 10.1177/1947601912466555
PUBMED: 23264850
PMCID: PMC3527989