Investigated event: Influence on gene expression

Name Value
Compound Paclitaxel
Investigated event Influence on gene expression
Experiment type ELISA
Concentration 0.30 mg/kg
Cell line kidney tissue
Organism Mus musculus
Animal model C57BL/6 (UUO)
STAT protein
Other IL-Iβ
Reference
Paclitaxel attenuates renal interstitial fibroblast activation and interstitial fibrosis by inhibiting STAT3 signaling. Drug design, development and therapy Lei Zhang, Xuan Xu, Ruhao Yang, Jingwen Chen, Shixuan Wang, Junqin Yang, Xudong Xiang, Zhibiao He, Yu Zhao, Zheng Dong, Dongshan Zhang, 9, None, None, 2015-04-15, 10.2147/DDDT.S81390 DOI: 10.2147/DDDT.S81390 PUBMED: 25931810 PMCID: PMC4404961