Investigated event: Influence on protein activity

Name Value
Compound LLL-12
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 5.00 µM
Cell line HSMM
Organism Homo sapiens
Animal model
STAT protein
Other GAPDH
Reference
Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice. Investigational new drugs Grace-Ifeyinwa Onimoe, Aiguo Liu, Li Lin, Chang-Ching Wei, Eric B Schwartz, Deepak Bhasin, Chenglong Li, James R Fuchs, Pui-kai Li, Peter Houghton, Amanda Termuhlen, Thomas Gross, Jiayuh Lin, 30, 3, None, 2011-02-22, 10.1007/s10637-011-9645-1 DOI: 10.1007/s10637-011-9645-1 PUBMED: 21340507 PMCID: 21340507