Investigated event: Influence on protein activity in tumor tissue
| Name | Value |
|---|---|
| Compound | LLL-12 |
| Investigated event | Influence on protein activity in tumor tissue |
| Experiment type | Western Blot |
| Concentration | 5.00 mg/kg |
| Cell line | MDA-MB-231 (xenograft) |
| Organism | Mus musculus |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. Neoplasia (New York, N.Y.) Li Lin, Brian Hutzen, Pui-Kai Li, Sarah Ball, Mingxin Zuo, Stephanie DeAngelis, Elizabeth Foust, Matthew Sobo, Lauren Friedman, Deepak Bhasin, Ling Cen, Chenglong Li, Jiayuh Lin, 12, 1, None, None, 10.1593/neo.91196
DOI: 10.1593/neo.91196
PUBMED: 20072652
PMCID: PMC2805882