Investigated event: Influence on gene expression

Name Value
Compound LLL-12
Investigated event Influence on gene expression
Experiment type RT-PCR
Concentration 10.00 µM
Cell line MDA-MB-231
Organism Homo sapiens
Animal model
STAT protein
Other GAPDH
Reference
A novel small molecule, LLL12, inhibits STAT3 phosphorylation and activities and exhibits potent growth-suppressive activity in human cancer cells. Neoplasia (New York, N.Y.) Li Lin, Brian Hutzen, Pui-Kai Li, Sarah Ball, Mingxin Zuo, Stephanie DeAngelis, Elizabeth Foust, Matthew Sobo, Lauren Friedman, Deepak Bhasin, Ling Cen, Chenglong Li, Jiayuh Lin, 12, 1, None, None, 10.1593/neo.91196 DOI: 10.1593/neo.91196 PUBMED: 20072652 PMCID: PMC2805882