Investigated event: Influence on angiogenesis
| Name | Value |
|---|---|
| Compound | Indirubin |
| Investigated event | Influence on angiogenesis |
| Experiment type | VEGF-induced mouse corneal model |
| Concentration | 10.00 mg/kg |
| Cell line | cornea |
| Organism | Mus musculus |
| Animal model | nude mice |
| STAT protein | |
| Other |
Reference
Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell. International journal of cancer Xiaoli Zhang, Yajuan Song, Yuanyuan Wu, Yanmin Dong, Li Lai, Jing Zhang, Binbin Lu, Fujun Dai, Lijun He, Mingyao Liu, Zhengfang Yi, 129, 10, 2011-11-15, 2011-04-07, 10.1002/ijc.25909
DOI: 10.1002/ijc.25909
PUBMED: 21207415
PMCID: 21207415