Investigated event: Influence on tumor growth

Name Value
Compound Indirubin
Investigated event Influence on tumor growth
Experiment type Body weight
Concentration 10.00 mg/kg
Cell line PC-3 (xenograft)
Organism Mus musculus
Animal model nude mice
STAT protein
Other
Reference
Indirubin inhibits tumor growth by antitumor angiogenesis via blocking VEGFR2-mediated JAK/STAT3 signaling in endothelial cell. International journal of cancer Xiaoli Zhang, Yajuan Song, Yuanyuan Wu, Yanmin Dong, Li Lai, Jing Zhang, Binbin Lu, Fujun Dai, Lijun He, Mingyao Liu, Zhengfang Yi, 129, 10, 2011-11-15, 2011-04-07, 10.1002/ijc.25909 DOI: 10.1002/ijc.25909 PUBMED: 21207415 PMCID: 21207415