Investigated event: Influence on apoptosis

Name Value
Compound HO-3867
Investigated event Influence on apoptosis
Experiment type Western Blot
Concentration 1.00 µM
Cell line Panc-1
Organism Homo sapiens
Animal model
STAT protein
Other pro-caspase-3
Reference
A novel STAT3 inhibitor HO-3867 induces cell apoptosis by reactive oxygen species-dependent endoplasmic reticulum stress in human pancreatic cancer cells. Anti-cancer drugs Yan Hu, Chengguang Zhao, Hailun Zheng, Kongqin Lu, Dengjian Shi, Zhiguo Liu, Xuanxuan Dai, Yi Zhang, Xiuhua Zhang, Wanle Hu, Guang Liang, 28, 4, None, None, 10.1097/CAD.0000000000000470 DOI: 10.1097/CAD.0000000000000470 PUBMED: 28067673 PMCID: 28067673