Investigated event: Influence on protein binding to DNA

Name Value
Compound FLL32
Investigated event Influence on protein binding to DNA
Experiment type ELISA
Concentration 10.00 µM
Cell line U266
Organism Homo sapiens
Animal model
STAT protein STAT3
Other
Reference
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells. Molecular cancer Li Lin, Stephanie Deangelis, Elizabeth Foust, James Fuchs, Chenglong Li, Pui-Kai Li, Eric B Schwartz, Gregory B Lesinski, Don Benson, Jiagao Lü, Dale Hoyt, Jiayuh Lin, 9, None, 2010-08-16, 2010-08-16, 10.1186/1476-4598-9-217 DOI: 10.1186/1476-4598-9-217 PUBMED: 20712901 PMCID: PMC2936338