Investigated event: Influence on protein activity

Name Value
Compound FLL32
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 5.00 µM
Cell line U266
Organism Homo sapiens
Animal model
STAT protein
Other p-JAK2 (Y1007/Y1008)
Reference
A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells. Molecular cancer Li Lin, Stephanie Deangelis, Elizabeth Foust, James Fuchs, Chenglong Li, Pui-Kai Li, Eric B Schwartz, Gregory B Lesinski, Don Benson, Jiagao Lü, Dale Hoyt, Jiayuh Lin, 9, None, 2010-08-16, 2010-08-16, 10.1186/1476-4598-9-217 DOI: 10.1186/1476-4598-9-217 PUBMED: 20712901 PMCID: PMC2936338