Investigated event: Influence on gene expression in presence of IFNγ

Name Value
Compound FLL32
Investigated event Influence on gene expression in presence of IFNγ
Experiment type RT-PCR
Concentration 4.00 µM
Cell line PBMC
Organism Homo sapiens
Animal model
STAT protein
Other IRF1
Reference
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular cancer Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski, 9, None, 2010-06-25, 2010-06-25, 10.1186/1476-4598-9-165 DOI: 10.1186/1476-4598-9-165 PUBMED: 20576164 PMCID: PMC2902420