Investigated event: Influence on protein activity in presence of IL-6

Name Value
Compound FLL32
Investigated event Influence on protein activity in presence of IL-6
Experiment type Western Blot
Concentration 10.00 µM
Cell line PBMC
Organism Homo sapiens
Animal model
STAT protein
Other β-actin
Reference
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular cancer Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski, 9, None, 2010-06-25, 2010-06-25, 10.1186/1476-4598-9-165 DOI: 10.1186/1476-4598-9-165 PUBMED: 20576164 PMCID: PMC2902420