Investigated event: Influence on protein activity in presence of IL-6
| Name | Value |
|---|---|
| Compound | FLL32 |
| Investigated event | Influence on protein activity in presence of IL-6 |
| Experiment type | Western Blot |
| Concentration | 8.00 µM |
| Cell line | PBMC |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | p-STAT3 |
| Other |
Reference
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular cancer Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski, 9, None, 2010-06-25, 2010-06-25, 10.1186/1476-4598-9-165
DOI: 10.1186/1476-4598-9-165
PUBMED: 20576164
PMCID: PMC2902420