Name	Value
Compound	FLL32
Investigated event	Influence on apoptosis
Experiment type	Western Blot
Concentration	4.00 µM
Cell line	primary human cells derived from recurrent cutaneous melanoma tumors
Organism	Homo sapiens
Animal model	patient 2
STAT protein
Other	Cyclin D1

The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular cancer Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski, 9, None, 2010-06-25, 2010-06-25, 10.1186/1476-4598-9-165 DOI: 10.1186/1476-4598-9-165 PUBMED: 20576164 PMCID: PMC2902420