Investigated event: Influence on apoptosis
Name | Value |
---|---|
Compound | FLL32 |
Investigated event | Influence on apoptosis |
Experiment type | Western Blot |
Concentration | 2.00 µM |
Cell line | primary human cells derived from recurrent cutaneous melanoma tumors |
Organism | Homo sapiens |
Animal model | patient 2 |
STAT protein | STAT3 |
Other |
Reference
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular cancer Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski, 9, None, 2010-06-25, 2010-06-25, 10.1186/1476-4598-9-165
DOI: 10.1186/1476-4598-9-165
PUBMED:
20576164
PMCID: PMC2902420