Investigated event: Influence on apoptosis

Name Value
Compound FLL32
Investigated event Influence on apoptosis
Experiment type Western Blot
Concentration 2.00 µM
Cell line primary human cells derived from recurrent cutaneous melanoma tumors
Organism Homo sapiens
Animal model patient 2
STAT protein
Other PARP
Reference
The small molecule curcumin analog FLLL32 induces apoptosis in melanoma cells via STAT3 inhibition and retains the cellular response to cytokines with anti-tumor activity. Molecular cancer Matthew A Bill, James R Fuchs, Chenglong Li, Jennifer Yui, Courtney Bakan, Don M Benson, Eric B Schwartz, Dalia Abdelhamid, Jiayuh Lin, Dale G Hoyt, Stacey L Fossey, Gregory S Young, William E Carson, Pui-Kai Li, Gregory B Lesinski, 9, None, 2010-06-25, 2010-06-25, 10.1186/1476-4598-9-165 DOI: 10.1186/1476-4598-9-165 PUBMED: 20576164 PMCID: PMC2902420