Investigated event: Influence on protein binding affinity to DNA
| Name | Value |
|---|---|
| Compound | FLL32 |
| Investigated event | Influence on protein binding affinity to DNA |
| Experiment type | EMSA |
| Concentration | 10.00 µM |
| Cell line | SJSA |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | STAT3 |
| Other |
Reference
The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. BMC cancer Stacey L Fossey, Misty D Bear, Jiayuh Lin, Chenglong Li, Eric B Schwartz, Pui-Kai Li, James R Fuchs, Joelle Fenger, William C Kisseberth, Cheryl A London, 11, None, 2011-03-28, 2011-03-28, 10.1186/1471-2407-11-112
DOI: 10.1186/1471-2407-11-112
PUBMED: 21443800
PMCID: PMC3074561