Investigated event: Influence on cell apoptosis

Name Value
Compound FLL32
Investigated event Influence on cell apoptosis
Experiment type SensoLyte® Homogeneous AMC Caspase-3/7 Assay
Concentration 7.50 µM
Cell line OSA8
Organism Canis lupus
Animal model
STAT protein
Other Caspase 3, 7 activity
Reference
The novel curcumin analog FLLL32 decreases STAT3 DNA binding activity and expression, and induces apoptosis in osteosarcoma cell lines. BMC cancer Stacey L Fossey, Misty D Bear, Jiayuh Lin, Chenglong Li, Eric B Schwartz, Pui-Kai Li, James R Fuchs, Joelle Fenger, William C Kisseberth, Cheryl A London, 11, None, 2011-03-28, 2011-03-28, 10.1186/1471-2407-11-112 DOI: 10.1186/1471-2407-11-112 PUBMED: 21443800 PMCID: PMC3074561