Investigated event: Influence on protein activity
| Name | Value |
|---|---|
| Compound | E738 |
| Investigated event | Influence on protein activity |
| Experiment type | Western Blot |
| Concentration | 1.00 µM |
| Cell line | Panc-1 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | p-JAK2 (Tyr1007/1008) |
Reference
Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells. Molecular oncology Sangkil Nam, Wei Wen, Anne Schroeder, Andreas Herrmann, Hua Yu, Xinlai Cheng, Karl-Heinz Merz, Gerhard Eisenbrand, Hongzhi Li, Yate-Ching Yuan, Richard Jove, 7, 3, None, 2012-11-16, 10.1016/j.molonc.2012.10.013
DOI: 10.1016/j.molonc.2012.10.013
PUBMED: 23206899
PMCID: PMC3968804