Investigated event: Influence on protein activity

Name Value
Compound E738
Investigated event Influence on protein activity
Experiment type Western Blot
Concentration 5.00 µM
Cell line BxPC3
Organism Homo sapiens
Animal model
STAT protein
Other p-Src (Tyr419)
Reference
Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells. Molecular oncology Sangkil Nam, Wei Wen, Anne Schroeder, Andreas Herrmann, Hua Yu, Xinlai Cheng, Karl-Heinz Merz, Gerhard Eisenbrand, Hongzhi Li, Yate-Ching Yuan, Richard Jove, 7, 3, None, 2012-11-16, 10.1016/j.molonc.2012.10.013 DOI: 10.1016/j.molonc.2012.10.013 PUBMED: 23206899 PMCID: PMC3968804