Investigated event: Influence on kinase activity
| Name | Value | 
|---|---|
| Compound | E738 | 
| Investigated event | Influence on kinase activity | 
| Experiment type | Kinase activity assay | 
| Concentration | 74.10 nM | 
| Cell line | |
| Organism | Homo sapiens | 
| Animal model | |
| STAT protein | |
| Other | JAK2 | 
            Reference
            
        
        Dual inhibition of Janus and Src family kinases by novel indirubin derivative blocks constitutively-activated Stat3 signaling associated with apoptosis of human pancreatic cancer cells. Molecular oncology Sangkil Nam, Wei Wen, Anne Schroeder, Andreas Herrmann, Hua Yu, Xinlai Cheng, Karl-Heinz Merz, Gerhard Eisenbrand, Hongzhi Li, Yate-Ching Yuan, Richard Jove, 7, 3, None, 2012-11-16, 10.1016/j.molonc.2012.10.013 
        DOI: 10.1016/j.molonc.2012.10.013 
        PUBMED: 23206899
        PMCID: PMC3968804 
    