Name	Value
Compound	Cucurbitacin B
Investigated event	Cytotoxicity effect
Experiment type	LDH release assay
Concentration	0.50 µM
Cell line	HT-29
Organism	Homo sapiens
Animal model
STAT protein
Other

Treatment with cucurbitacin B alone and in combination with gefitinib induces cell cycle inhibition and apoptosis via EGFR and JAK/STAT pathway in human colorectal cancer cell lines. Human & experimental toxicology A S Yar Saglam, E Alp, Z Elmazoglu, S Menevse, 35, 5, None, 2015-07-16, 10.1177/0960327115595686 DOI: 10.1177/0960327115595686 PUBMED: 26183715 PMCID: 26183715