Investigated event: Influence on protein activity

Name Value
Compound Cucurbitacin E
Investigated event Influence on protein activity
Experiment type Chromatin immunoprecipitation assay
Concentration 10.00 nM
Cell line PC3
Organism Homo sapiens
Animal model
STAT protein
Other β-actin
Reference
Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway. Carcinogenesis Yanmin Dong, Binbin Lu, Xiaoli Zhang, Jing Zhang, Li Lai, Dali Li, Yuanyuan Wu, Yajuan Song, Jian Luo, Xiufeng Pang, Zhengfang Yi, Mingyao Liu, 31, 12, None, 2010-08-23, 10.1093/carcin/bgq167 DOI: 10.1093/carcin/bgq167 PUBMED: 20732905 PMCID: 20732905