Investigated event: Influence on protein activity
| Name | Value |
|---|---|
| Compound | Cucurbitacin E |
| Investigated event | Influence on protein activity |
| Experiment type | Chromatin immunoprecipitation assay |
| Concentration | 1.00 nM |
| Cell line | PC3 |
| Organism | Homo sapiens |
| Animal model | |
| STAT protein | |
| Other | Bcl-xL |
Reference
Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway. Carcinogenesis Yanmin Dong, Binbin Lu, Xiaoli Zhang, Jing Zhang, Li Lai, Dali Li, Yuanyuan Wu, Yajuan Song, Jian Luo, Xiufeng Pang, Zhengfang Yi, Mingyao Liu, 31, 12, None, 2010-08-23, 10.1093/carcin/bgq167
DOI: 10.1093/carcin/bgq167
PUBMED: 20732905
PMCID: 20732905