Investigated event: Influence on tumor angiogenesis
| Name | Value |
|---|---|
| Compound | Cucurbitacin E |
| Investigated event | Influence on tumor angiogenesis |
| Experiment type | Immunohistochemistry |
| Concentration | 3.00 mg/kg |
| Cell line | PC3(xenograft) |
| Organism | Mus musculus |
| Animal model | c57BL/6 |
| STAT protein | |
| Other |
Reference
Cucurbitacin E, a tetracyclic triterpenes compound from Chinese medicine, inhibits tumor angiogenesis through VEGFR2-mediated Jak2-STAT3 signaling pathway. Carcinogenesis Yanmin Dong, Binbin Lu, Xiaoli Zhang, Jing Zhang, Li Lai, Dali Li, Yuanyuan Wu, Yajuan Song, Jian Luo, Xiufeng Pang, Zhengfang Yi, Mingyao Liu, 31, 12, None, 2010-08-23, 10.1093/carcin/bgq167
DOI: 10.1093/carcin/bgq167
PUBMED: 20732905
PMCID: 20732905