Investigated event: Influence on protein activity

Name Value
Compound Cucurbitacin I
Investigated event Influence on protein activity
Experiment type Luciferase activity
Concentration 0.50 µM
Cell line Microglia
Organism Homo sapiens
Animal model
STAT protein
Other ARE/HO-1
Reference
Cucurbitacins attenuate microglial activation and protect from neuroinflammatory injury through Nrf2/ARE activation and STAT/NF-κB inhibition. Neuroscience letters Sun Young Park, Young Hun Kim, Geuntae Park, 609, None, 2015-11-16, 2015-10-22, 10.1016/j.neulet.2015.10.022 DOI: 10.1016/j.neulet.2015.10.022 PUBMED: 26472707 PMCID: 26472707