Investigated event: Influence on protein activity in tumor tissue
| Name | Value |
|---|---|
| Compound | Cryptotanshinone |
| Investigated event | Influence on protein activity in tumor tissue |
| Experiment type | Immunohistochemistry |
| Concentration | 60.00 mg/kg |
| Cell line | U87 (xenograft) |
| Organism | Mus musculus |
| Animal model | BALB/c |
| STAT protein | p-STAT3(Y705) |
| Other |
Reference
Cryptotanshinone inhibits human glioma cell proliferation in vitro and in vivo through SHP-2-dependent inhibition of STAT3 activation. Cell death & disease Liang Lu, Sulin Zhang, Cuixian Li, Chun Zhou, Dong Li, Peiqing Liu, Min Huang, Xiaoyan Shen, 8, 5, 2017-05-11, 2017-05-11, 10.1038/cddis.2017.174.
DOI: 10.1038/cddis.2017.174.
PUBMED: 28492557
PMCID: PMC5520699