Investigated event: Influence on gene expression levels in presence of CLI and/or EPO
| Name | Value |
|---|---|
| Compound | AG490 |
| Investigated event | Influence on gene expression levels in presence of CLI and/or EPO |
| Experiment type | RT-qPCR |
| Concentration | 3.00 mg/kg |
| Cell line | quadriceps |
| Organism | Rattus norvegicus |
| Animal model | Sprague-Dawley (SD) rats |
| STAT protein | |
| Other | IL-10 |
Reference
AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemia. Journal of inflammation (London, England) Han-Tan Chai, Hon-Kan Yip, Cheuk-Kwan Sun, Shu-Yuan Hsu, Steve Leu, 13, None, None, 2016-06-04, 10.1186/s12950-016-0126-3
DOI: 10.1186/s12950-016-0126-3
PUBMED: 27274711
PMCID: PMC4893245